A mechanism of chlorothiazide-enhanced effectiveness of antihypertensive ganglioplegic drugs.
نویسندگان
چکیده
('hlorothiazide decreases plasma volume, heart size, and cardiac output. The oligeamii stimulates vasomotor tone; this tends to maintain arterial pressure because chronic arterial hypertension is characteristically self-sustaining and homeostatic. This oligenmic stimulation of vasomotor tone results in increased sensitivity to the antihypertensivQe effect of drugs depressing or blocking vasomotor function.
منابع مشابه
Mechanism of the antihypertensive effects of diuretics. Possible role of salt in hypertension.
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ورودعنوان ژورنال:
- Circulation
دوره 19 3 شماره
صفحات -
تاریخ انتشار 1959